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doi: 10.1186/s13046-024-03032-9 30 WangXLiuPAnYHuYQiaoHMiaoH

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Numerous animal models have been created to investigate AD, including vertebrate transgenic rodents, invertebrates such as zebrafish and Drosophila melanogaster , as well as naturally occurring models in NHPs and dogs (Figure 4)

NHPN-1010 is a fixed combination product consisting of two antioxidants, i.e., N-acetylcysteine (NAC, a glutathione prodrug) and 2,4-disulfophenyl-N-tert-butylnitrone (HPN-07, a nitrone compound)